When I diagnose Mast Cell Activation Syndrome (MCAS), I use the Consensus 2 criteria. This method moves beyond the traditional tryptase-level criteria of Consensus 1, and focuses instead on symptom charts, response to treatment and specific lab tests. I’ve found this method to work impeccably. Many practitioners are not aware of mast cell activation syndrome and the complexity of how it can present, or either continue to use the outdated Consensus 1 approach or, worse, revert to an understanding
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Diagnosing MCAS requires more than just tests. Mast Cell Activation often begins during puberty, which is why a detailed history of symptoms, responses to antihistamines, and triggers like stress or certain medications all help paint the bigger picture. Tests alone can’t reveal the root cause – it's the patient’s story that provides real clues. Module 2 of my New Medical Curriculum is entirely dedicated to MCAS and POTS. Comment LEARN for the free masterclass. Disclaimer: The information shared
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