The meaning of SUBSTANCE is essential nature : essence. How to use substance in a sentence.

SUBSTANCE meaning: 1 : a material of a particular kind; 2 : a drug that is considered harmful and whose use is controlled by law or made illegal

An ecosystem is a system controlled by the flow of energy, and substances such as water, carbon and phosphorus, exchanged among living things.

Definition of substance noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

Substance is the quality of being important or significant. It's questionable whether anything of substance has been achieved. Syria will attend only if the negotiations deal with issues of …

A drug, chemical, or other material (such as glue) that one is dependent on or uses habitually and that is often illegal or subject to government regulation: Which substance was he abusing? 2. …

Some chemical substances can be combined or converted into new substances by means of chemical reactions. Chemicals that do not possess this ability are said to be inert. Pure water …

Chemistry a particular kind of material, as of a definite chemical composition:[countable] a metallic substance. substantial, important, significant, or solid character or quality:[uncountable] Those …

Any material that possesses physical properties is called a substance. The word also refers to the gist or main idea of something. If you remember the main point of a lesson, you've got the …

Dec 14, 2025 · substance (countable and uncountable, plural substances) Physical matter; material. quotations