Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth [1] and is also used to reduce the pain of intramuscular …

Procaine causes loss of feeling (numbness) of skin and mucous membranes. Procaine is used as an injection during surgery and other medical and dental procedures.

As a prescription-only injection, procaine is used for local anesthesia. Procaine works as an anesthetic when injected. However, procaine doesn't get absorbed well when it is taken by mouth.

Procaine is taken by mouth or given as a shot for arthritis, “hardening of the arteries” in the brain (cerebral atherosclerosis), dementia, depression, hair loss, high blood pressure, and sexual …

May 8, 2023 · This activity reviews the indications, mechanism of action, adverse effects, contraindications, administration, and monitoring of procaine use in applications of local, regional, …

Dec 19, 2025 · Procaine hydrochloride, synthetic organic compound used in medicine as a local anesthetic. Introduced in 1905 under the trade name Novocaine, it became the first and best-known …

Procaine is defined as a local analgesic introduced in 1905, primarily used to replace cocaine, and characterized by poor mucous membrane penetration and a slow onset of nerve block following …

Procaine is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Procaine (like cocaine) has the advantage of constricting blood vessels which reduces …

Aug 1, 2025 · Procaine is a synthetic organic compound classified as an ester-type local anesthetic. Introduced in 1905, it was one of the earliest synthetic local anesthetics developed. It became widely …

Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the …