An aging mouse forgets where the hidden platform sits in a water maze. But strip away a single iron-storage protein from its hippocampal neurons, and the animal navigates like a younger version of ...
Inborn errors of metabolism (IEMs) are rare, devastating disorders caused by pathogenic variants in genes encoding key metabolic enzymes, with the liver playing a critical role in over 140 IEMs. Liver ...
Most people think of Alzheimer’s disease as an illness of aging. But in fact, the brain changes that characterize it begin much earlier – sometime around the third decade of life. Developing tau ...