Q: What is reversed-phase LC? Answer: Reversed-phase LC is a powerful tool for characterizing mAbs and biosimilars. It is used with UV detectors in QC monitoring and product release testing, and with ...

Figure 1: Schematic representation of the continuous FFE apparatus coupled off-line to RP-HPLC. Hydroxypropyl methyl cellulose (HPMC) stock solution, 2% (wt/vol; ∼86 K nominal molecular weight; ...

Ionic and ionizable compounds typically rely on separation by ion exchange chromatography (IC) or ion pairing reversed-phase chromatography (IP-RPLC). In traditional Reverse-phase Liquid ...

Antibody-drug conjugates (ADCs) are cancer therapeutics that harness the targeting abilities of monoclonal antibodies to deliver small-molecule drugs directly to tumors. Characterization of such ...

Chromatography is an analytical technique that is used to separate and analyze complex mixtures. Chromatography works by distributing the components of a mixture between two phases, known as the ...