Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...
Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...
MONMOUTH JUNCTION, N.J., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Tris Pharma, Inc. (Tris), a commercial-stage biopharmaceutical company, today announced the acceptance of its peer-reviewed article "The ...
New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.
For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...
Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...
Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...
To date, therapies for multiple sclerosis (MS) focus on modifying or suppressing the immune system rather than on remyelination. Recent findings have pointed to the κ-opioid receptor (KOR) as a ...
– Study met primary endpoint demonstrating cebranopadol is significantly less abusable than oxycodone when taken intranasally (i.e., snorted) with majority of patients indicating no desire to take ...