Enhancer sequences increase gene transcription with the help of a co-activator complex, the Mediator. Another protein complex — cohesin — seems to work with Mediator to bring together enhancers and ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 2 (Jan. 19, 1999), pp. 376-381 (6 pages) The mediator complex is essential for regulated transcription in ...

Journal of Experimental Botany, Vol. 70, No. 13, Special Issue: What Jasmonates and other Oxylipins do for Plants (15 June 2019), pp. 3415-3424 (10 pages) The Mediator complex is an essential, ...

The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (RNAPII), governs the expression of all protein-coding and most non-coding ...

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be ...

A new study advances existing knowledge about transcription and gene expression. This multi-institution team of researchers made interesting discoveries about the role of the Mediator protein complex ...

Sequence-specific, DNA-binding TFs are the major regulators of cell identity and cell physiology. As examples, expression of select TFs can revert differentiated cells back to a pluripotent state and ...

DNA, the long polymer curled up inside our cells, is often described as the instructions for life. But those instructions are stored in DNA’s chemical code, and reading that code requires the ...

Did you know that the DNA in any cell of the human body - or any organism for that matter - contains the genetic information required to develop every possible type of cell within that organism? Yet ...