Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Scientists have published a ground-breaking study of the structure and function of a central protein in the liver: NTCP, a cellular-entry pathway for bile salts, but also for certain hepatitis viruses ...

Researchers report that pairing two known medicines reduced liver fibrosis in mice, offering a possible path toward scar ...

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the ...

Liver enzymes can fluctuate due to factors like hormonal changes or reactions to medications. Fluctuations are often temporary, but long-term changes may indicate a condition that requires medical ...

Fatty liver disease is rarely a standalone diagnosis: A doctor breaking the news of positive test results will probably be someone you’re already seeing for another chronic condition. It can be either ...

Though an essential gateway to the liver, NTCP had not been well described until now. Na+-taurocholate co-transporting polypeptide (NTCP) is a protein located exclusively in the membrane of liver ...