White light interferometry (WLI) is a contact-free optical method for measuring surface height. It uses the phase difference between the light reflected off a reference mirror and the target sample to ...

Most conventional light microscopes have a resolution of 200 nanometers – this means that imaged objects which are any closer together won't be seen as separate items. A new high-tech microscope slide ...

Engineers have developed a technology that turns a conventional light microscope into what's called a super-resolution microscope. It improves the microscope's resolution (from 200 nm to 40 nm) so ...

The M25 multi-focus microscope uses separate cameras to capture images from 25 focal planes at different depths in a sample. (Photo by Eduardo Hirata) The aberration-corrected multi-focus microscopy ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Using a “spooky” phenomenon of quantum physics, Caltech researchers have discovered a way to double the resolution of light microscopes. In a paper appearing in the journal Nature Communications, a ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...