Medical therapy is an established first-line approach for the treatment of patients with chronic anal fissure; however, the efficacy of individual agents versus placebo remains to be proven in this ...

Current treatments for anal fissures focus on reducing the tone of the internal anal sphincter, whether by sphincterotomy, injection of botulinum toxin or the topical application of nitroglycerin or ...

Treating an anal fissure typically involves practices that help the area heal, like using a sitz bath or taking stool softeners. Other times a doctor may recommend medication or a medical procedure.

Chronic anal fissures are tears in the tissue of the anal canal that last for more than 8 weeks. Unlike acute fissures that often heal on their own, chronic anal fissures require medical treatment.