Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders ...
In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia. Hypoxia arises as tumors grow rapidly, outpacing their ...
Researchers have found evidence that low oxygen levels in tumors could actually enhance some of the body's immune responses against cancer, in contrast with the general paradigm that hypoxia ...