TECHNOLOGY for reinforcing the α-helix, a familiar protein motif throughout biology, could lead to a new class of peptide-based drugs. Because of their particular blend of chemical properties, ...
Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units ...
Chemistry professor Samuel H. Gellman and postdoc Tomohisa Sawada of the University of Wisconsin, Madison, demonstrated the approach by making a 12-amino acid peptide from one β-, one γ-, and 10 ...
Solving puzzles experimentally is enjoyable for many researchers. However, there are some puzzles that force even the best puzzlers to nominate modeling over experimental approaches to help decipher ...