A simpler, cost-effective method for the preparation of fluorolactams may be suitable for scale-up. The incorporation of fluorine into APIs continues to be a key approach to improving important ...

Researchers at GlaxoSmithKline report a greener and lower-cost route to chiral fluorolactams that is suitable for scale up. PM Images/GETTY IMAGES The incorporation of fluorine into APIs continues to ...

(Nanowerk News) Researchers from Tohoku University and collaborators have developed a weak fluorination strategy to address the zero-bandgap limitation of graphene. The findings are published in ...

Tasked with improving the biological profile of drug candidates, medicinal chemists treasure reactions that easily slip a fluorine atom onto a molecule. That’s because the addition of this little ...

Researchers from the Muñiz group have published a paper in Angewandte Chemie - International Edition presenting a new metal-free methodology for the photo-catalysed nucleophilic fluorination of ...

Cytochrome P450 enzymes selectively oxidize relatively unactivated sites in a range of model drug-like substrates in vitro. The hydroxylated products can be transformed into selectively fluorinated ...

Fluorination of therapeutic agents is a widely used strategy in the pharmaceutical industry. It improves a drug’s molecular properties, such as drug-target interactions, bioavailability, and ...

Researchers synthesized a fluorinated electron-acceptor for use in organic semiconductors. The high electronegativity of the fluorine substituents enhanced the electron-accepting properties of the ...

A unanimous federal appeals court March 21 tossed out an Environmental Protection Agency order that would have shut down the plastic container fluorination process of Inhance Technologies LLC. The ...