Nanomedicine. 2014;9(1):105-120. Overall, HDL-based siRNA delivery possesses many attractive features, including ultra-small size, favorable surface properties (no PEGylation is required for achieving ...
Lipid-based nanoparticles are a popular research area as a non-viral platform for delivering RNA molecules and include liposomes, lipoplexes, lipid nanoparticles and solid lipid nanoparticles. Using ...
Lipid nanoparticles (LNPs) have enormous potential for the delivery of genomic medicine. One obstacle, however, is the lack of effective ways to target specific cell types. In order to target lung ...
A recent study published in Small explored how cationic fusogenic liposomes can merge directly with cellular membranes to improve drug delivery. Researchers found that these liposomes can temporarily ...
Schematic illustration showing the classification of lipid‐based nanocarriers (LBNCs) (including liposomes, micelles, nanoemulsions, SLNs/NLCs, LNPs, BLNs, SRLNCs) and their targeted delivery to ...
A recent perspective article published in the journal Nature Reviews Drug Discovery discussed the evolution of lipid nanoparticles (LNPs) for nucleic acid delivery. The authors, Pieter Cullis, ...
Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network. The ...