High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...
When no more solute can be dissolved in a solvent the solution is said to be saturated. Each different substance has a different solubility. This table shows the solubility of substances in water at ...
Modern methods and modeling offer a better way to understand solubility issues and solve today’s complex formulation challenges. Poor solubility is an ongoing challenge in pharmaceutical development.
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