In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA ...

A team of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Seville, in collaboration with the Virgen Macarena University Hospital, ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

Using comparative molecular biology with human cGAS – which actually inhibits DNA repair – the scientists found that the naked mole-rat's enzyme has four key changes that facilitate the important work ...