The management of chronic anal fissure has received renewed interest and has been re-evaluated over the past 20 years. The use of botulinum toxin seems to be a promising and safe approach, ...

Medical therapy is an established first-line approach for the treatment of patients with chronic anal fissure; however, the efficacy of individual agents versus placebo remains to be proven in this ...

A digital rectal exam, which may be painful, may be needed if a definitive diagnosis of anal fissures cannot be made based on a patient’s history. 1 Anoscopy, which also may be painful, can be used to ...

An anal fissure is a small tear in the thin, moist tissue (mucosa) that lines the anus. An anal fissure may occur when you pass hard or large stools during a bowel movement. Anal fissures typically ...