Most multiphoton microscopy studies to date use genetically engineered animals that express fluorescent proteins in cells of interest to detect and follow their fate in the tissue. Although very ...

Immunofluorescence is a common technique in modern biology and medicine. It is a highly sensitive method used primarily for the analysis of tissue samples with a fluorescence microscope. When this ...

Diagnostic instrumentation that provides autofluorescence capabilities is helping clinicians diagnose retinal conditions earlier by showing abnormalities that are often invisible to standard fundus ...

Fundus autofluorescence patterns observed using confocal scanning laser ophthalmoscopy may be linked to disease progression in patients with age-related macular degeneration and may thereby help ...

A team led by Vanderbilt University and Vanderbilt University Medical Center biomedical engineers and surgeons has published results of a large clinical trial showing that use of a near-infrared ...

Researchers headed by a team at the University of Wisconsin (UW)-Madison, and the Morgridge Institute for Research, have developed a novel label-free imaging technique that exploits autofluorescence ...

Uveitis, or inflammation of the eye's uvea area beneath the white of the eye, is a rare disease that has proven challenging to diagnose and monitor. A team from University Hospital Bonn (UKB) and ...

Healing of chronic wounds requires sterile conditions and avoidance of infections. But methods for detecting the "bioburden," or quantity and types of bacteria present, are imperfect. Semiquantitative ...

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in ...

More than 6.5 million Americans suffer from chronic wounds that do not heal within a few months. Many of these wounds are infected with bacteria, and if left untreated, they can lead to serious ...

TrueVIEW removes unwanted autofluorescence in tissue sections due to aldehyde fixation, red blood cells, and structural elements such as collagen and elastin, improving overall signal-to-noise in most ...